Use of dimiracetam in the treatment of chronic pai

专利名称：Use of dimiracetam in the treatment of

chronic pain

发明人：Farina, Carlo,Ghelardini, Carla,Petrillo, Paola申请号：EP13002151.2申请日：20080415公开号：EP2620149A3公开日：20130807

摘要：The use of dimiracetam in the treatment of chronic pain chronic pain induced byosteoarthritis, rheumatoid arthritis or autoimmune osteoarthrosis forms is disclosed. Atdoses higher than those previously disclosed in relation with its cognition enhancingactivity (i.e. amelioration of learning and memory), dimiracetam was able to completelyrevert hyperalgesia or allodynia associated with several animal models of chronic pain.Dimiracetam showed high activity in painful conditions caused by osteoarthritis. In

addition, dimiracetam was devoid of toxicity even at doses 10-fold higher than the highesttherapeutic dose. The possibility of treating such debilitating pathologies with a highlyeffective and essentially non-toxic compound is therefore disclosed.

申请人：Neurotune AG

地址：Wagistrasse 27a 52 Schlieren CH

国籍：CH

代理机构：Rüedi, Regula Béatrice

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